BDBM50245214 CHEMBL4065590

SMILES: CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1F)C(F)(F)F

InChI Key: InChIKey=BYNGHBDIDRZYKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DCN1-UBC12 (Homo sapiens)	BDBM50245214 (CHEMBL4065590 | US11116757, No. A70) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1F)C(F)(F)F Show InChI InChI=1S/C24H29F4N3O/c1-2-3-14-30-15-12-19(13-16-30)31(17-18-8-5-4-6-9-18)23(32)29-21-11-7-10-20(22(21)25)24(26,27)28/h4-11,19H,2-3,12-17H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245214 (CHEMBL4065590 | US11116757, No. A70) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1F)C(F)(F)F Show InChI InChI=1S/C24H29F4N3O/c1-2-3-14-30-15-12-19(13-16-30)31(17-18-8-5-4-6-9-18)23(32)29-21-11-7-10-20(22(21)25)24(26,27)28/h4-11,19H,2-3,12-17H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair