BDBM50245223 CHEMBL4085483
SMILES: CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F
InChI Key: InChIKey=WCGOOMQGWKQUSZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DCN1-UBC12 (Homo sapiens) | BDBM50245223 (CHEMBL4085483 | US11116757, No. A26) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 163 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DCN1-like protein 1 (Homo sapiens) | BDBM50245223 (CHEMBL4085483 | US11116757, No. A26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 612 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a... | J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ | |||||||||||
More data for this Ligand-Target Pair |