BDBM50245249 CHEMBL452584::N-(Benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester

SMILES: COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key: InChIKey=MXMAVZMWYSUCJZ-SFTDATJTSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50245249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50245249 (CHEMBL452584 | N-(Benzyloxycarbonyl)-L-leucyl-L-ph...) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H30N2O5/c1-17(2)14-20(26-24(29)31-16-19-12-8-5-9-13-19)22(27)25-21(23(28)30-3)15-18-10-6-4-7-11-18/h4-13,17,20-21H,14-16H2,1-3H3,(H,25,27)(H,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50245249 (CHEMBL452584 | N-(Benzyloxycarbonyl)-L-leucyl-L-ph...) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H30N2O5/c1-17(2)14-20(26-24(29)31-16-19-12-8-5-9-13-19)22(27)25-21(23(28)30-3)15-18-10-6-4-7-11-18/h4-13,17,20-21H,14-16H2,1-3H3,(H,25,27)(H,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50245249 (CHEMBL452584 | N-(Benzyloxycarbonyl)-L-leucyl-L-ph...) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H30N2O5/c1-17(2)14-20(26-24(29)31-16-19-12-8-5-9-13-19)22(27)25-21(23(28)30-3)15-18-10-6-4-7-11-18/h4-13,17,20-21H,14-16H2,1-3H3,(H,25,27)(H,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50245249 (CHEMBL452584 | N-(Benzyloxycarbonyl)-L-leucyl-L-ph...) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H30N2O5/c1-17(2)14-20(26-24(29)31-16-19-12-8-5-9-13-19)22(27)25-21(23(28)30-3)15-18-10-6-4-7-11-18/h4-13,17,20-21H,14-16H2,1-3H3,(H,25,27)(H,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP3				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50245249 (CHEMBL452584 | N-(Benzyloxycarbonyl)-L-leucyl-L-ph...) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H30N2O5/c1-17(2)14-20(26-24(29)31-16-19-12-8-5-9-13-19)22(27)25-21(23(28)30-3)15-18-10-6-4-7-11-18/h4-13,17,20-21H,14-16H2,1-3H3,(H,25,27)(H,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP7				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50245249 (CHEMBL452584 | N-(Benzyloxycarbonyl)-L-leucyl-L-ph...) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C24H30N2O5/c1-17(2)14-20(26-24(29)31-16-19-12-8-5-9-13-19)22(27)25-21(23(28)30-3)15-18-10-6-4-7-11-18/h4-13,17,20-21H,14-16H2,1-3H3,(H,25,27)(H,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2				Eur J Med Chem 43: 1008-14 (2008) Article DOI: 10.1016/j.ejmech.2007.07.002 BindingDB Entry DOI: 10.7270/Q23T9H1W
					More data for this Ligand-Target Pair