BDBM50245682 9-Dimethylamino-3-(1H-indol-6-yl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::CHEMBL455415

SMILES: CN(C)c1ccnc2sc3c(ncn(-c4ccc5cc[nH]c5c4)c3=O)c12

InChI Key: InChIKey=YYFOGNITDRWPJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50245682 (9-Dimethylamino-3-(1H-indol-6-yl)-3H-pyrido[3',2':...) Show SMILES CN(C)c1ccnc2sc3c(ncn(-c4ccc5cc[nH]c5c4)c3=O)c12 Show InChI InChI=1S/C19H15N5OS/c1-23(2)14-6-8-21-18-15(14)16-17(26-18)19(25)24(10-22-16)12-4-3-11-5-7-20-13(11)9-12/h3-10,20H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Biocampus Curated by ChEMBL					Assay Description Inhibition of rat mGluR1				Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM
					More data for this Ligand-Target Pair