BDBM50245785 2-(4-((3-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-5-carboxamido)methyl)-2-methylphenoxy)-2-methylpropanoic acid::CHEMBL509680
SMILES: CCn1nc(cc1C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1)-c1ccc(cc1)C(C)(C)C
InChI Key: InChIKey=OTOWLPBTZHONBE-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50245785 (2-(4-((3-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha receptor by cell based transient transfection assay | Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50245785 (2-(4-((3-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma receptor by cell based transient transfection assay | Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50245785 (2-(4-((3-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Agonist activity at human PPARdelta receptor by cell based transient transfection assay | Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H | |||||||||||
More data for this Ligand-Target Pair |