BDBM50245843 2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-3-carboxamido)methyl)-2-methylphenoxy)-2-methylpropanoic acid::CHEMBL460278

SMILES: CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1

InChI Key: InChIKey=AUKXWOYKKNDADD-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50245843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50245843 (2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) Show SMILES CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 Show InChI InChI=1S/C28H35N3O4/c1-8-31-23(20-10-12-21(13-11-20)27(3,4)5)16-22(30-31)25(32)29-17-19-9-14-24(18(2)15-19)35-28(6,7)26(33)34/h9-16H,8,17H2,1-7H3,(H,29,32)(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha receptor by cell based transient transfection assay				Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50245843 (2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) Show SMILES CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 Show InChI InChI=1S/C28H35N3O4/c1-8-31-23(20-10-12-21(13-11-20)27(3,4)5)16-22(30-31)25(32)29-17-19-9-14-24(18(2)15-19)35-28(6,7)26(33)34/h9-16H,8,17H2,1-7H3,(H,29,32)(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta receptor by cell based transient transfection assay				Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50245843 (2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) Show SMILES CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 Show InChI InChI=1S/C28H35N3O4/c1-8-31-23(20-10-12-21(13-11-20)27(3,4)5)16-22(30-31)25(32)29-17-19-9-14-24(18(2)15-19)35-28(6,7)26(33)34/h9-16H,8,17H2,1-7H3,(H,29,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at mouse PPARgamma receptor by cell based transient transfection assay				Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50245843 (2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) Show SMILES CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 Show InChI InChI=1S/C28H35N3O4/c1-8-31-23(20-10-12-21(13-11-20)27(3,4)5)16-22(30-31)25(32)29-17-19-9-14-24(18(2)15-19)35-28(6,7)26(33)34/h9-16H,8,17H2,1-7H3,(H,29,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at mouse PPARalpha receptor by cell based transient transfection assay				Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50245843 (2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) Show SMILES CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 Show InChI InChI=1S/C28H35N3O4/c1-8-31-23(20-10-12-21(13-11-20)27(3,4)5)16-22(30-31)25(32)29-17-19-9-14-24(18(2)15-19)35-28(6,7)26(33)34/h9-16H,8,17H2,1-7H3,(H,29,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at mouse PPARdelta receptor by cell based transient transfection assay				Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50245843 (2-(4-((5-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-...) Show SMILES CCn1nc(cc1-c1ccc(cc1)C(C)(C)C)C(=O)NCc1ccc(OC(C)(C)C(O)=O)c(C)c1 Show InChI InChI=1S/C28H35N3O4/c1-8-31-23(20-10-12-21(13-11-20)27(3,4)5)16-22(30-31)25(32)29-17-19-9-14-24(18(2)15-19)35-28(6,7)26(33)34/h9-16H,8,17H2,1-7H3,(H,29,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma receptor by cell based transient transfection assay				Bioorg Med Chem Lett 18: 6251-4 (2008) Article DOI: 10.1016/j.bmcl.2008.09.094 BindingDB Entry DOI: 10.7270/Q20Z733H
					More data for this Ligand-Target Pair