BDBM50245929 CHEMBL517867::N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-yl)furan-2-carboxamide

SMILES: O=C(Nc1nc2ccccc2c2cn(nc12)-c1ccccc1)c1ccco1

InChI Key: InChIKey=FAGWLARBSJETTC-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50245929 (CHEMBL517867 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...) Show SMILES O=C(Nc1nc2ccccc2c2cn(nc12)-c1ccccc1)c1ccco1 Show InChI InChI=1S/C21H14N4O2/c26-21(18-11-6-12-27-18)23-20-19-16(15-9-4-5-10-17(15)22-20)13-25(24-19)14-7-2-1-3-8-14/h1-13H,(H,22,23,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 401-10 (2008) Article DOI: 10.1016/j.bmc.2008.10.018 BindingDB Entry DOI: 10.7270/Q21N810X
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50245929 (CHEMBL517867 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...) Show SMILES O=C(Nc1nc2ccccc2c2cn(nc12)-c1ccccc1)c1ccco1 Show InChI InChI=1S/C21H14N4O2/c26-21(18-11-6-12-27-18)23-20-19-16(15-9-4-5-10-17(15)22-20)13-25(24-19)14-7-2-1-3-8-14/h1-13H,(H,22,23,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...				Bioorg Med Chem 17: 401-10 (2008) Article DOI: 10.1016/j.bmc.2008.10.018 BindingDB Entry DOI: 10.7270/Q21N810X
					More data for this Ligand-Target Pair