BDBM50246104 CHEMBL512174::N-(4-(3-chloro-4-methoxybenzylamino)-7-methoxy-8-propylquinazolin-6-yl)-2,2,2-trifluoroacetamide

SMILES: CCCc1c(OC)c(NC(=O)C(F)(F)F)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12

InChI Key: InChIKey=VENMPUTVGFIXPY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50246104 (CHEMBL512174 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)C(F)(F)F)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C22H22ClF3N4O3/c1-4-5-13-18-14(9-16(19(13)33-3)30-21(31)22(24,25)26)20(29-11-28-18)27-10-12-6-7-17(32-2)15(23)8-12/h6-9,11H,4-5,10H2,1-3H3,(H,30,31)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of bovine PDE5				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair
Phosphodiesterase 11A (Homo sapiens (Human))	BDBM50246104 (CHEMBL512174 | N-(4-(3-chloro-4-methoxybenzylamino...) Show SMILES CCCc1c(OC)c(NC(=O)C(F)(F)F)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 Show InChI InChI=1S/C22H22ClF3N4O3/c1-4-5-13-18-14(9-16(19(13)33-3)30-21(31)22(24,25)26)20(29-11-28-18)27-10-12-6-7-17(32-2)15(23)8-12/h6-9,11H,4-5,10H2,1-3H3,(H,30,31)(H,27,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE11				Bioorg Med Chem Lett 18: 6279-82 (2008) Article DOI: 10.1016/j.bmcl.2008.09.108 BindingDB Entry DOI: 10.7270/Q2SB45MV
					More data for this Ligand-Target Pair