BDBM50246958 1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-ethylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine::CHEMBL507816

SMILES: CCc1cc(ccc1CNC(=O)Nc1c(F)cccc1F)C(=O)N1CCCCc2ccccc12

InChI Key: InChIKey=DGBUVSLRNXAUMV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246958   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50246958 (1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-ethylb...) Show SMILES CCc1cc(ccc1CNC(=O)Nc1c(F)cccc1F)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C27H27F2N3O2/c1-2-18-16-20(26(33)32-15-6-5-9-19-8-3-4-12-24(19)32)13-14-21(18)17-30-27(34)31-25-22(28)10-7-11-23(25)29/h3-4,7-8,10-14,16H,2,5-6,9,15,17H2,1H3,(H2,30,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair