BDBM50247064 1-(4-[N-(2-Amino-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine::CHEMBL462409

SMILES: Cc1cc(ccc1CNC(=O)NCC(N)=O)C(=O)N1CCCCc2ccccc12

InChI Key: InChIKey=PADZCOVJJWXXCN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50247064 (1-(4-[N-(2-Amino-2-oxoethylcarbamoyl)aminomethyl]-...) Show SMILES Cc1cc(ccc1CNC(=O)NCC(N)=O)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C22H26N4O3/c1-15-12-17(9-10-18(15)13-24-22(29)25-14-20(23)27)21(28)26-11-5-4-7-16-6-2-3-8-19(16)26/h2-3,6,8-10,12H,4-5,7,11,13-14H2,1H3,(H2,23,27)(H2,24,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
Vantia Ltd Curated by ChEMBL					Assay Description Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...				J Med Chem 51: 8124-34 (2008) Article DOI: 10.1021/jm8008162 BindingDB Entry DOI: 10.7270/Q28W3D6V
					More data for this Ligand-Target Pair