BDBM50247290 CHEMBL489477::N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(2-fluorobiphenyl-4-yl)acetamide

SMILES: Fc1cc(CC(=O)Nc2cc(n[nH]2)C2CC2)ccc1-c1ccccc1

InChI Key: InChIKey=ZXSYFAVSCAKWOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50247290 (CHEMBL489477 | N-(5-cyclopropyl-1H-pyrazol-3-yl)-2...) Show SMILES Fc1cc(CC(=O)Nc2cc(n[nH]2)C2CC2)ccc1-c1ccccc1 Show InChI InChI=1S/C20H18FN3O/c21-17-10-13(6-9-16(17)14-4-2-1-3-5-14)11-20(25)22-19-12-18(23-24-19)15-7-8-15/h1-6,9-10,12,15H,7-8,11H2,(H2,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology (CSIR) Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin A (unknown origin)				Eur J Med Chem 43: 2807-18 (2008) Article DOI: 10.1016/j.ejmech.2007.10.016 BindingDB Entry DOI: 10.7270/Q2MP5324
					More data for this Ligand-Target Pair