BDBM50247678 (+/-)-3-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethylchroman-4-ylcarbamate::CHEMBL455407

SMILES: CC1(C)Oc2ccc(cc2C(NC(=O)c2cccc(Cl)c2)C1O)C#N

InChI Key: InChIKey=NCSBMDAOMUEETK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sulfonylurea receptor 2, Kir6.2 (Homo sapiens (Human))	BDBM50247678 ((+/-)-3-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethy...) Show SMILES CC1(C)Oc2ccc(cc2C(NC(=O)c2cccc(Cl)c2)C1O)C#N Show InChI InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-8-11(10-21)6-7-15(14)25-19)22-18(24)12-4-3-5-13(20)9-12/h3-9,16-17,23H,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR				Bioorg Med Chem 17: 855-66 (2009) Article DOI: 10.1016/j.bmc.2008.11.055 BindingDB Entry DOI: 10.7270/Q2N017FM
					More data for this Ligand-Target Pair