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SMILES: CC1(C)Oc2ccc(cc2[C@@H](Nc2n[nH]c3ccc(Cl)cc23)[C@@H]1O)C#N

InChI Key: InChIKey=XKOTZGGOROIHCO-SJORKVTESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247783   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-binding cassette sub-family C member 9


(Homo sapiens (Human))		BDBM50247783
PNG
((3S,4R)-4-(5-Chloro-1H-indazol-3-ylamino)-3-hydrox...)
Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2n[nH]c3ccc(Cl)cc23)[C@@H]1O)C#N |r|
Show InChI InChI=1S/C19H17ClN4O2/c1-19(2)17(25)16(13-7-10(9-21)3-6-15(13)26-19)22-18-12-8-11(20)4-5-14(12)23-24-18/h3-8,16-17,25H,1-2H3,(H2,22,23,24)/t16-,17+/m1/s1
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PC cid
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Article
PubMed
n/an/an/an/a 6.85E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR

Bioorg Med Chem 17: 855-66 (2009)


Article DOI: 10.1016/j.bmc.2008.11.055
BindingDB Entry DOI: 10.7270/Q2N017FM
More data for this
Ligand-Target Pair