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SMILES: CC1(C)Oc2ccc(cc2[C@@H](Nc2noc3ccc(Cl)cc23)[C@@H]1O)S(=O)(=O)c1cccc(F)c1

InChI Key: InChIKey=FFFFDRTWHXOYSL-YADHBBJMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247785   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-binding cassette sub-family C member 9


(Homo sapiens (Human))		BDBM50247785
PNG
((3S,4R)-4-(5-Chloro-benzo[d]isoxazol-3-ylamino)-6-...)
Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Nc2noc3ccc(Cl)cc23)[C@@H]1O)S(=O)(=O)c1cccc(F)c1 |r|
Show InChI InChI=1S/C24H20ClFN2O5S/c1-24(2)22(29)21(27-23-18-10-13(25)6-8-20(18)33-28-23)17-12-16(7-9-19(17)32-24)34(30,31)15-5-3-4-14(26)11-15/h3-12,21-22,29H,1-2H3,(H,27,28)/t21-,22+/m1/s1
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Article
PubMed
n/an/an/an/a 7.77E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR

Bioorg Med Chem 17: 855-66 (2009)


Article DOI: 10.1016/j.bmc.2008.11.055
BindingDB Entry DOI: 10.7270/Q2N017FM
More data for this
Ligand-Target Pair