BDBM50248268 (+/-)-2-cyclopropyl-N-((1S)-3-(4-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)piperidin-1-yl)-1-phenylbutyl)acetamide::CHEMBL515261

SMILES: CC(C)c1nnc(C)n1C1CCN(CC1)C(C)C[C@H](NC(=O)CC1CC1)c1ccccc1

InChI Key: InChIKey=XKUZAOLNXRKIRL-WIIYFNMSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50248268 ((+/-)-2-cyclopropyl-N-((1S)-3-(4-(3-isopropyl-5-me...) Show SMILES CC(C)c1nnc(C)n1C1CCN(CC1)C(C)C[C@H](NC(=O)CC1CC1)c1ccccc1 |r| Show InChI InChI=1S/C26H39N5O/c1-18(2)26-29-28-20(4)31(26)23-12-14-30(15-13-23)19(3)16-24(22-8-6-5-7-9-22)27-25(32)17-21-10-11-21/h5-9,18-19,21,23-24H,10-17H2,1-4H3,(H,27,32)/t19?,24-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...				Bioorg Med Chem Lett 19: 1499-503 (2009) Article DOI: 10.1016/j.bmcl.2009.01.008 BindingDB Entry DOI: 10.7270/Q2PN96JF
					More data for this Ligand-Target Pair