BDBM50249355 2-(2-aminoethylamino)-4-(3-ethylphenylamino)pyrimidine-5-carboxamide::CHEMBL512328

SMILES: CCc1cccc(Nc2nc(NCCN)ncc2C(N)=O)c1

InChI Key: InChIKey=JDQNHTVXBDXOQH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50249355 (2-(2-aminoethylamino)-4-(3-ethylphenylamino)pyrimi...) Show SMILES CCc1cccc(Nc2nc(NCCN)ncc2C(N)=O)c1 Show InChI InChI=1S/C15H20N6O/c1-2-10-4-3-5-11(8-10)20-14-12(13(17)22)9-19-15(21-14)18-7-6-16/h3-5,8-9H,2,6-7,16H2,1H3,(H2,17,22)(H2,18,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair