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SMILES: Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ccc2C(N)=O)c1

InChI Key: InChIKey=GLYDOFDMRWDEDQ-JKSUJKDBSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249543   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM50249543
PNG
(6-((1R,2S)-2-aminocyclohexylamino)-2-(m-tolylamino...)
Show SMILES Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ccc2C(N)=O)c1 |r|
Show InChI InChI=1S/C19H25N5O/c1-12-5-4-6-13(11-12)22-19-14(18(21)25)9-10-17(24-19)23-16-8-3-2-7-15(16)20/h4-6,9-11,15-16H,2-3,7-8,20H2,1H3,(H2,21,25)(H2,22,23,24)/t15-,16+/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant Syk (unknown origin)

Bioorg Med Chem Lett 19: 1944-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.049
BindingDB Entry DOI: 10.7270/Q2WM1D98
More data for this
Ligand-Target Pair