BDBM50249703 CHEMBL4079841

SMILES: CCCCNc1nc(N)nc2ccn(Cc3ccsc3)c12

InChI Key: InChIKey=FWFMRIXKRQWPAJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50249703 (CHEMBL4079841) Show SMILES CCCCNc1nc(N)nc2ccn(Cc3ccsc3)c12 Show InChI InChI=1S/C15H19N5S/c1-2-3-6-17-14-13-12(18-15(16)19-14)4-7-20(13)9-11-5-8-21-10-11/h4-5,7-8,10H,2-3,6,9H2,1H3,(H3,16,17,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium. Curated by ChEMBL					Assay Description Agonist activity at TLR7 in human PBMC assessed as induction of IFNalpha-mediated inhibition of HCV genotype 1b RNA replication in human HuH luc/neo ...				J Med Chem 60: 6137-6151 (2017) Article DOI: 10.1021/acs.jmedchem.7b00365 BindingDB Entry DOI: 10.7270/Q2XP77CC
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