BDBM50249951 CHEMBL4059969

SMILES: CC(C)COC(=O)c1ccc(NC(=O)c2ccncc2)cc1

InChI Key: InChIKey=VXQCPUCWXDPWHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homeobox protein Nkx-2.5/Transcription factor GATA-4 (Mus musculus)	BDBM50249951 (CHEMBL4059969) Show SMILES CC(C)COC(=O)c1ccc(NC(=O)c2ccncc2)cc1 Show InChI InChI=1S/C17H18N2O3/c1-12(2)11-22-17(21)14-3-5-15(6-4-14)19-16(20)13-7-9-18-10-8-13/h3-10,12H,11H2,1-2H3,(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki , Helsinki FI-00014, Finland. Curated by ChEMBL					Assay Description Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...				J Med Chem 60: 7781-7798 (2017) Article DOI: 10.1021/acs.jmedchem.7b00816 BindingDB Entry DOI: 10.7270/Q2DN47GK
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