BDBM50251011 CHEMBL2397398

SMILES: Oc1ccc(cc1)-c1nc2sc3CCCCCc3c2c(=O)[nH]1

InChI Key: InChIKey=HIPCDHDMFWCRML-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50251011 (CHEMBL2397398) Show SMILES Oc1ccc(cc1)-c1nc2sc3CCCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O2S/c20-11-8-6-10(7-9-11)15-18-16(21)14-12-4-2-1-3-5-13(12)22-17(14)19-15/h6-9,20H,1-5H2,(H,18,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...				J Med Chem 56: 5436-45 (2013) Article DOI: 10.1021/jm400405z BindingDB Entry DOI: 10.7270/Q2B27Z7S
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50251011 (CHEMBL2397398) Show SMILES Oc1ccc(cc1)-c1nc2sc3CCCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C17H16N2O2S/c20-11-8-6-10(7-9-11)15-18-16(21)14-12-4-2-1-3-5-13(12)22-17(14)19-15/h6-9,20H,1-5H2,(H,18,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...				J Med Chem 60: 9990-10012 (2017) Article DOI: 10.1021/acs.jmedchem.7b00275 BindingDB Entry DOI: 10.7270/Q2M32Z68
					More data for this Ligand-Target Pair