BDBM50251032 CHEMBL4104274

SMILES: O=c1[nH]c(Cc2ccc(cc2)-c2ccccc2)nc2sc3CCCCCc3c12

InChI Key: InChIKey=RFPDXISRRBBOEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50251032 (CHEMBL4104274) Show SMILES O=c1[nH]c(Cc2ccc(cc2)-c2ccccc2)nc2sc3CCCCCc3c12 Show InChI InChI=1S/C24H22N2OS/c27-23-22-19-9-5-2-6-10-20(19)28-24(22)26-21(25-23)15-16-11-13-18(14-12-16)17-7-3-1-4-8-17/h1,3-4,7-8,11-14H,2,5-6,9-10,15H2,(H,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...				J Med Chem 60: 9990-10012 (2017) Article DOI: 10.1021/acs.jmedchem.7b00275 BindingDB Entry DOI: 10.7270/Q2M32Z68
					More data for this Ligand-Target Pair