BDBM50251502 CHEMBL4103831

SMILES: Nc1cc(ccn1)-c1c[nH]c2cc(ccc12)C(F)(F)F

InChI Key: InChIKey=NPPYMINKJWTKBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50251502 (CHEMBL4103831) Show SMILES Nc1cc(ccn1)-c1c[nH]c2cc(ccc12)C(F)(F)F Show InChI InChI=1S/C14H10F3N3/c15-14(16,17)9-1-2-10-11(7-20-12(10)6-9)8-3-4-19-13(18)5-8/h1-7,20H,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of full-length recombinant human GST-tagged Dyrk1a expressed in baculovirus expression system using Alexa-Fluor tracer-236 incubated for 6...				Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP
					More data for this Ligand-Target Pair