BDBM50251507 CHEMBL4094549
SMILES: Nc1cc(ccn1)-c1c[nH]c2c(cccc12)[N+]([O-])=O
InChI Key: InChIKey=AOYZBAOTPDCTNT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human)) | BDBM50251507![]() (CHEMBL4094549) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 285 | n/a | n/a | n/a | n/a | n/a | n/a |
Rigel Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of full-length recombinant human GST-tagged Dyrk1a expressed in baculovirus expression system using Alexa-Fluor tracer-236 incubated for 6... | Bioorg Med Chem Lett 27: 2617-2621 (2017) Article DOI: 10.1016/j.bmcl.2017.03.037 BindingDB Entry DOI: 10.7270/Q2SN0CFP | |||||||||||
More data for this Ligand-Target Pair |