BDBM50251726 6-(3-(trifluoromethyl)phenylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole::CHEMBL481278
SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)n1c2CCNCCc2c2ccccc12
InChI Key: InChIKey=CCAVKHAOUJAWHT-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50251726 (6-(3-(trifluoromethyl)phenylsulfonyl)-1,2,3,4,5,6-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cells | Bioorg Med Chem Lett 18: 3929-31 (2008) Article DOI: 10.1016/j.bmcl.2008.06.030 BindingDB Entry DOI: 10.7270/Q2959HCP | |||||||||||
More data for this Ligand-Target Pair |