null

SMILES: OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3)cc2)cc1

InChI Key: InChIKey=SOBBPXNTLJAPSJ-BKFWDETESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50251745 (CHEMBL520596 | endo-4-((3-(4-phenoxyphenylamino)-8...) Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C27H28N2O3/c30-27(31)20-8-6-19(7-9-20)18-29-23-12-13-24(29)17-22(16-23)28-21-10-14-26(15-11-21)32-25-4-2-1-3-5-25/h1-11,14-15,22-24,28H,12-13,16-18H2,(H,30,31)/t22-,23+,24-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in human whole blood				Bioorg Med Chem Lett 18: 3895-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.041 BindingDB Entry DOI: 10.7270/Q2GQ6XK8
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50251745 (CHEMBL520596 | endo-4-((3-(4-phenoxyphenylamino)-8...) Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C27H28N2O3/c30-27(31)20-8-6-19(7-9-20)18-29-23-12-13-24(29)17-22(16-23)28-21-10-14-26(15-11-21)32-25-4-2-1-3-5-25/h1-11,14-15,22-24,28H,12-13,16-18H2,(H,30,31)/t22-,23+,24-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase (unknown origin)				Bioorg Med Chem Lett 18: 3895-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.041 BindingDB Entry DOI: 10.7270/Q2GQ6XK8
					More data for this Ligand-Target Pair