BDBM50251818 (2S,4S)-1-(2-((1S,5R,6s)-3-(2-cyano-3,5-difluorophenyl)-3-aza-bicyclo[3.1.0]hexan-6-ylamino)acetyl)-4-fluoropyrrolidine-2-carbonitrile::CHEMBL520921

SMILES: F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1cc(F)cc(F)c1C#N

InChI Key: InChIKey=OOUJXBPKJBAPMD-NEYKFGMSSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50251818 ((2S,4S)-1-(2-((1S,5R,6s)-3-(2-cyano-3,5-difluoroph...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1cc(F)cc(F)c1C#N |r| Show InChI InChI=1S/C19H18F3N5O/c20-10-2-16(22)13(5-24)17(3-10)26-8-14-15(9-26)19(14)25-6-18(28)27-7-11(21)1-12(27)4-23/h2-3,11-12,14-15,19,25H,1,6-9H2/t11-,12-,14-,15+,19+/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human plasma DPP4				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50251818 ((2S,4S)-1-(2-((1S,5R,6s)-3-(2-cyano-3,5-difluoroph...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1cc(F)cc(F)c1C#N |r| Show InChI InChI=1S/C19H18F3N5O/c20-10-2-16(22)13(5-24)17(3-10)26-8-14-15(9-26)19(14)25-6-18(28)27-7-11(21)1-12(27)4-23/h2-3,11-12,14-15,19,25H,1,6-9H2/t11-,12-,14-,15+,19+/m0/s1	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50251818 ((2S,4S)-1-(2-((1S,5R,6s)-3-(2-cyano-3,5-difluoroph...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1cc(F)cc(F)c1C#N |r| Show InChI InChI=1S/C19H18F3N5O/c20-10-2-16(22)13(5-24)17(3-10)26-8-14-15(9-26)19(14)25-6-18(28)27-7-11(21)1-12(27)4-23/h2-3,11-12,14-15,19,25H,1,6-9H2/t11-,12-,14-,15+,19+/m0/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PPCE (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50251818 ((2S,4S)-1-(2-((1S,5R,6s)-3-(2-cyano-3,5-difluoroph...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1cc(F)cc(F)c1C#N |r| Show InChI InChI=1S/C19H18F3N5O/c20-10-2-16(22)13(5-24)17(3-10)26-8-14-15(9-26)19(14)25-6-18(28)27-7-11(21)1-12(27)4-23/h2-3,11-12,14-15,19,25H,1,6-9H2/t11-,12-,14-,15+,19+/m0/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP2 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50251818 ((2S,4S)-1-(2-((1S,5R,6s)-3-(2-cyano-3,5-difluoroph...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1cc(F)cc(F)c1C#N |r| Show InChI InChI=1S/C19H18F3N5O/c20-10-2-16(22)13(5-24)17(3-10)26-8-14-15(9-26)19(14)25-6-18(28)27-7-11(21)1-12(27)4-23/h2-3,11-12,14-15,19,25H,1,6-9H2/t11-,12-,14-,15+,19+/m0/s1	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair