BDBM50251850 CHEMBL4077816

SMILES: Cc1ccc(CNC2CCc3c(C2)[nH]c2ccccc32)cc1

InChI Key: InChIKey=CPAIEIJZVFXFPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-tagged Rb (Homo sapiens (Human))	BDBM50251850 (CHEMBL4077816) Show SMILES Cc1ccc(CNC2CCc3c(C2)[nH]c2ccccc32)cc1 Show InChI InChI=1S/C20H22N2/c1-14-6-8-15(9-7-14)13-21-16-10-11-18-17-4-2-3-5-19(17)22-20(18)12-16/h2-9,16,21-22H,10-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Padmashri Vikhe Patil College of Arts Curated by ChEMBL					Assay Description Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assay				Eur J Med Chem 134: 366-378 (2017) Article DOI: 10.1016/j.ejmech.2017.02.062 BindingDB Entry DOI: 10.7270/Q2MW2KKK
					More data for this Ligand-Target Pair