BDBM50251852 (2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-yl)-3-aza-bicyclo[3.1.0]hexan-6-ylamino)acetyl)pyrrolidine-2-carbonitrile::CHEMBL482261

SMILES: F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ncccn1

InChI Key: InChIKey=NXGCDTBNUXWSGM-XOBFJNJYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50251852 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-y...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ncccn1 |r| Show InChI InChI=1S/C16H19FN6O/c17-10-4-11(5-18)23(7-10)14(24)6-21-15-12-8-22(9-13(12)15)16-19-2-1-3-20-16/h1-3,10-13,15,21H,4,6-9H2/t10-,11-,12-,13+,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human plasma DPP4				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50251852 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-y...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ncccn1 |r| Show InChI InChI=1S/C16H19FN6O/c17-10-4-11(5-18)23(7-10)14(24)6-21-15-12-8-22(9-13(12)15)16-19-2-1-3-20-16/h1-3,10-13,15,21H,4,6-9H2/t10-,11-,12-,13+,15+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50251852 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-y...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ncccn1 |r| Show InChI InChI=1S/C16H19FN6O/c17-10-4-11(5-18)23(7-10)14(24)6-21-15-12-8-22(9-13(12)15)16-19-2-1-3-20-16/h1-3,10-13,15,21H,4,6-9H2/t10-,11-,12-,13+,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PPCE (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50251852 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-y...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ncccn1 |r| Show InChI InChI=1S/C16H19FN6O/c17-10-4-11(5-18)23(7-10)14(24)6-21-15-12-8-22(9-13(12)15)16-19-2-1-3-20-16/h1-3,10-13,15,21H,4,6-9H2/t10-,11-,12-,13+,15+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP2 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50251852 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(pyrimidin-2-y...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ncccn1 |r| Show InChI InChI=1S/C16H19FN6O/c17-10-4-11(5-18)23(7-10)14(24)6-21-15-12-8-22(9-13(12)15)16-19-2-1-3-20-16/h1-3,10-13,15,21H,4,6-9H2/t10-,11-,12-,13+,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair