null

SMILES: F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F

InChI Key: InChIKey=CCAHGNFSCCVYCY-QHUBEEEXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50251853 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F |r| Show InChI InChI=1S/C17H18F4N6O/c18-9-3-10(4-22)27(6-9)14(28)5-24-15-11-7-26(8-12(11)15)16-23-2-1-13(25-16)17(19,20)21/h1-2,9-12,15,24H,3,5-8H2/t9-,10-,11-,12+,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human plasma DPP4				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50251853 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F |r| Show InChI InChI=1S/C17H18F4N6O/c18-9-3-10(4-22)27(6-9)14(28)5-24-15-11-7-26(8-12(11)15)16-23-2-1-13(25-16)17(19,20)21/h1-2,9-12,15,24H,3,5-8H2/t9-,10-,11-,12+,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50251853 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F |r| Show InChI InChI=1S/C17H18F4N6O/c18-9-3-10(4-22)27(6-9)14(28)5-24-15-11-7-26(8-12(11)15)16-23-2-1-13(25-16)17(19,20)21/h1-2,9-12,15,24H,3,5-8H2/t9-,10-,11-,12+,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PPCE (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50251853 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F |r| Show InChI InChI=1S/C17H18F4N6O/c18-9-3-10(4-22)27(6-9)14(28)5-24-15-11-7-26(8-12(11)15)16-23-2-1-13(25-16)17(19,20)21/h1-2,9-12,15,24H,3,5-8H2/t9-,10-,11-,12+,15+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP2 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50251853 ((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...) Show SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F |r| Show InChI InChI=1S/C17H18F4N6O/c18-9-3-10(4-22)27(6-9)14(28)5-24-15-11-7-26(8-12(11)15)16-23-2-1-13(25-16)17(19,20)21/h1-2,9-12,15,24H,3,5-8H2/t9-,10-,11-,12+,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ranbaxy Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9 (unknown origin)				Bioorg Med Chem Lett 18: 4087-91 (2008) Article DOI: 10.1016/j.bmcl.2008.05.101 BindingDB Entry DOI: 10.7270/Q2T153FC
					More data for this Ligand-Target Pair