null

SMILES: CCSC(=S)SCC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1

InChI Key: InChIKey=GUGUEEIYRWQGRW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50252008 (2-(4-Benzenesulfonylamino-phenyl)-2-oxoethyl ethyl...) Show SMILES CCSC(=S)SCC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H17NO3S4/c1-2-23-17(22)24-12-16(19)13-8-10-14(11-9-13)18-25(20,21)15-6-4-3-5-7-15/h3-11,18H,2,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cells				J Med Chem 51: 3985-4001 (2008) Article DOI: 10.1021/jm800093c BindingDB Entry DOI: 10.7270/Q29886S0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50252008 (2-(4-Benzenesulfonylamino-phenyl)-2-oxoethyl ethyl...) Show SMILES CCSC(=S)SCC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H17NO3S4/c1-2-23-17(22)24-12-16(19)13-8-10-14(11-9-13)18-25(20,21)15-6-4-3-5-7-15/h3-11,18H,2,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cells				J Med Chem 51: 3985-4001 (2008) Article DOI: 10.1021/jm800093c BindingDB Entry DOI: 10.7270/Q29886S0
					More data for this Ligand-Target Pair