null

SMILES: CCSC(=S)SCC(=O)c1ccc(Nc2ncnc3ccccc23)cc1

InChI Key: InChIKey=ZQTBIZBQRGUXFG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50252055 (CHEMBL482094 | Ethyl 2-oxo-2-[4-(quinazolin-4-ylam...) Show SMILES CCSC(=S)SCC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 Show InChI InChI=1S/C19H17N3OS3/c1-2-25-19(24)26-11-17(23)13-7-9-14(10-8-13)22-18-15-5-3-4-6-16(15)20-12-21-18/h3-10,12H,2,11H2,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cells				J Med Chem 51: 3985-4001 (2008) Article DOI: 10.1021/jm800093c BindingDB Entry DOI: 10.7270/Q29886S0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50252055 (CHEMBL482094 | Ethyl 2-oxo-2-[4-(quinazolin-4-ylam...) Show SMILES CCSC(=S)SCC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 Show InChI InChI=1S/C19H17N3OS3/c1-2-25-19(24)26-11-17(23)13-7-9-14(10-8-13)22-18-15-5-3-4-6-16(15)20-12-21-18/h3-10,12H,2,11H2,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cells				J Med Chem 51: 3985-4001 (2008) Article DOI: 10.1021/jm800093c BindingDB Entry DOI: 10.7270/Q29886S0
					More data for this Ligand-Target Pair