BDBM50252510 CHEMBL4076413

SMILES: Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC=C(C)C1)C(O)=O

InChI Key: InChIKey=UAXANUPFKSSNSO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP1 receptor (Rattus norvegicus (Rat))	BDBM50252510 (CHEMBL4076413) Show SMILES Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC=C(C)C1)C(O)=O |t:23| Show InChI InChI=1S/C19H19ClN4O2S/c1-11-4-3-5-23(9-11)19-21-17-13(7-14(20)8-16(17)27-19)10-24-12(2)6-15(22-24)18(25)26/h4,6-8H,3,5,9-10H2,1-2H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Watarase Research Center, Discovery Research Headquarters, Kyorin Pharmaceutical Co., Ltd., 1848, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan. Curated by ChEMBL					Assay Description Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...				Bioorg Med Chem 25: 3406-3430 (2017) Article DOI: 10.1016/j.bmc.2017.04.028 BindingDB Entry DOI: 10.7270/Q2JW8HB8
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