BDBM50252719 (S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimidin-2,4-dione::CHEMBL493892

SMILES: N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O

InChI Key: InChIKey=CAXDSUJFJPXUEH-YFKPBYRVSA-N

Data: 6 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252719 ((S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimid...) Show SMILES N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O |r| Show InChI InChI=1S/C9H9N3O5/c10-5(8(14)15)1-12-6-3-17-2-4(6)7(13)11-9(12)16/h2-3,5H,1,10H2,(H,14,15)(H,11,13,16)/t5-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50252719 ((S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimid...) Show SMILES N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O |r| Show InChI InChI=1S/C9H9N3O5/c10-5(8(14)15)1-12-6-3-17-2-4(6)7(13)11-9(12)16/h2-3,5H,1,10H2,(H,14,15)(H,11,13,16)/t5-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50252719 ((S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimid...) Show SMILES N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O |r| Show InChI InChI=1S/C9H9N3O5/c10-5(8(14)15)1-12-6-3-17-2-4(6)7(13)11-9(12)16/h2-3,5H,1,10H2,(H,14,15)(H,11,13,16)/t5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	4.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair				3D Structure (crystal)
GRIA3 (RAT)	BDBM50252719 ((S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimid...) Show SMILES N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O |r| Show InChI InChI=1S/C9H9N3O5/c10-5(8(14)15)1-12-6-3-17-2-4(6)7(13)11-9(12)16/h2-3,5H,1,10H2,(H,14,15)(H,11,13,16)/t5-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50252719 ((S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimid...) Show SMILES N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O |r| Show InChI InChI=1S/C9H9N3O5/c10-5(8(14)15)1-12-6-3-17-2-4(6)7(13)11-9(12)16/h2-3,5H,1,10H2,(H,14,15)(H,11,13,16)/t5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50252719 ((S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimid...) Show SMILES N[C@@H](Cn1c2cocc2c(=O)[nH]c1=O)C(O)=O |r| Show InChI InChI=1S/C9H9N3O5/c10-5(8(14)15)1-12-6-3-17-2-4(6)7(13)11-9(12)16/h2-3,5H,1,10H2,(H,14,15)(H,11,13,16)/t5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair