BDBM50252749 3-chloro-N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]methyl}benzamide::CHEMBL493680

SMILES: CC(C)(C)CCN1CCC(CNC(=O)c2cccc(Cl)c2)CC1

InChI Key: InChIKey=DGCIYURXAGZZSS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50252749 (3-chloro-N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]m...) Show SMILES CC(C)(C)CCN1CCC(CNC(=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C19H29ClN2O/c1-19(2,3)9-12-22-10-7-15(8-11-22)14-21-18(23)16-5-4-6-17(20)13-16/h4-6,13,15H,7-12,14H2,1-3H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50252749 (3-chloro-N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]m...) Show SMILES CC(C)(C)CCN1CCC(CNC(=O)c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C19H29ClN2O/c1-19(2,3)9-12-22-10-7-15(8-11-22)14-21-18(23)16-5-4-6-17(20)13-16/h4-6,13,15H,7-12,14H2,1-3H3,(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPR				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair