BDBM50252750 5-bromo-N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]methyl}nicotinamide::CHEMBL493879

SMILES: CC(C)(C)CCN1CCC(CNC(=O)c2cncc(Br)c2)CC1

InChI Key: InChIKey=GSFIKAIQXNMAJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50252750 (5-bromo-N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]me...) Show SMILES CC(C)(C)CCN1CCC(CNC(=O)c2cncc(Br)c2)CC1 Show InChI InChI=1S/C18H28BrN3O/c1-18(2,3)6-9-22-7-4-14(5-8-22)11-21-17(23)15-10-16(19)13-20-12-15/h10,12-14H,4-9,11H2,1-3H3,(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPR				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair