BDBM50252791 3,5-dichloro-N-({1-[3-(trifluoromethyl)benzyl]piperidin-4-yl}methyl)benzamide::CHEMBL523525

SMILES: FC(F)(F)c1cccc(CN2CCC(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)c1

InChI Key: InChIKey=NWKDHMOLGIJQDW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50252791 (3,5-dichloro-N-({1-[3-(trifluoromethyl)benzyl]pipe...) Show SMILES FC(F)(F)c1cccc(CN2CCC(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)c1 Show InChI InChI=1S/C21H21Cl2F3N2O/c22-18-9-16(10-19(23)11-18)20(29)27-12-14-4-6-28(7-5-14)13-15-2-1-3-17(8-15)21(24,25)26/h1-3,8-11,14H,4-7,12-13H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50252791 (3,5-dichloro-N-({1-[3-(trifluoromethyl)benzyl]pipe...) Show SMILES FC(F)(F)c1cccc(CN2CCC(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)c1 Show InChI InChI=1S/C21H21Cl2F3N2O/c22-18-9-16(10-19(23)11-18)20(29)27-12-14-4-6-28(7-5-14)13-15-2-1-3-17(8-15)21(24,25)26/h1-3,8-11,14H,4-7,12-13H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPR				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair