BDBM50252848 (R)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2-hydroxybenzyl)-3,4-dichlorophenylethylamino)-2-propanol::CHEMBL522530

SMILES: CS(=O)(=O)Nc1ccc(OC[C@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccccc2O)cc1

InChI Key: InChIKey=PVNKTEVKLYEYIV-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252848 ((R)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2-hydrox...) Show SMILES CS(=O)(=O)Nc1ccc(OC[C@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccccc2O)cc1 |r| Show InChI InChI=1S/C25H28Cl2N2O5S/c1-35(32,33)28-20-7-9-22(10-8-20)34-17-21(30)16-29(15-19-4-2-3-5-25(19)31)13-12-18-6-11-23(26)24(27)14-18/h2-11,14,21,28,30-31H,12-13,15-17H2,1H3/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	433	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...				J Med Chem 51: 5506-21 (2008) Article DOI: 10.1021/jm8002153 BindingDB Entry DOI: 10.7270/Q2PZ59QH
					More data for this Ligand-Target Pair