BDBM50252919 (S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-2,4(3H,5H)-dione::CHEMBL492628

SMILES: N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O

InChI Key: InChIKey=RPYXYQHRAXAOCI-UWVGGRQHSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50252919 ((S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydr...) Show SMILES N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O |r| Show InChI InChI=1S/C15H22N4O6/c16-9(13(21)22)4-6-18-11-3-1-2-8(11)12(20)19(15(18)25)7-5-10(17)14(23)24/h9-10H,1-7,16-17H2,(H,21,22)(H,23,24)/t9-,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50252919 ((S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydr...) Show SMILES N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O |r| Show InChI InChI=1S/C15H22N4O6/c16-9(13(21)22)4-6-18-11-3-1-2-8(11)12(20)19(15(18)25)7-5-10(17)14(23)24/h9-10H,1-7,16-17H2,(H,21,22)(H,23,24)/t9-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50252919 ((S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydr...) Show SMILES N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O |r| Show InChI InChI=1S/C15H22N4O6/c16-9(13(21)22)4-6-18-11-3-1-2-8(11)12(20)19(15(18)25)7-5-10(17)14(23)24/h9-10H,1-7,16-17H2,(H,21,22)(H,23,24)/t9-,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50252919 ((S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydr...) Show SMILES N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O |r| Show InChI InChI=1S/C15H22N4O6/c16-9(13(21)22)4-6-18-11-3-1-2-8(11)12(20)19(15(18)25)7-5-10(17)14(23)24/h9-10H,1-7,16-17H2,(H,21,22)(H,23,24)/t9-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50252919 ((S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydr...) Show SMILES N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O |r| Show InChI InChI=1S/C15H22N4O6/c16-9(13(21)22)4-6-18-11-3-1-2-8(11)12(20)19(15(18)25)7-5-10(17)14(23)24/h9-10H,1-7,16-17H2,(H,21,22)(H,23,24)/t9-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50252919 ((S,S)-1,3-Di(3'-amino-3'-carboxypropyl)-6,7-dihydr...) Show SMILES N[C@@H](CCn1c2CCCc2c(=O)n(CC[C@H](N)C(O)=O)c1=O)C(O)=O |r| Show InChI InChI=1S/C15H22N4O6/c16-9(13(21)22)4-6-18-11-3-1-2-8(11)12(20)19(15(18)25)7-5-10(17)14(23)24/h9-10H,1-7,16-17H2,(H,21,22)(H,23,24)/t9-,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair