BDBM50253241 (S)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2,3,4-trifluorobenzyl)-3,4-dichlorophenylethylamino)-2-propanol::CHEMBL493078

SMILES: CS(=O)(=O)Nc1ccc(OC[C@@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccc(F)c(F)c2F)cc1

InChI Key: InChIKey=SVZCHDXRIPMIIX-IBGZPJMESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50253241 ((S)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2,3,4-tr...) Show SMILES CS(=O)(=O)Nc1ccc(OC[C@@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccc(F)c(F)c2F)cc1 |r| Show InChI InChI=1S/C25H25Cl2F3N2O4S/c1-37(34,35)31-18-4-6-20(7-5-18)36-15-19(33)14-32(11-10-16-2-8-21(26)22(27)12-16)13-17-3-9-23(28)25(30)24(17)29/h2-9,12,19,31,33H,10-11,13-15H2,1H3/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG expressed in HEK293 cells				J Med Chem 51: 5506-21 (2008) Article DOI: 10.1021/jm8002153 BindingDB Entry DOI: 10.7270/Q2PZ59QH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50253241 ((S)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2,3,4-tr...) Show SMILES CS(=O)(=O)Nc1ccc(OC[C@@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccc(F)c(F)c2F)cc1 |r| Show InChI InChI=1S/C25H25Cl2F3N2O4S/c1-37(34,35)31-18-4-6-20(7-5-18)36-15-19(33)14-32(11-10-16-2-8-21(26)22(27)12-16)13-17-3-9-23(28)25(30)24(17)29/h2-9,12,19,31,33H,10-11,13-15H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...				J Med Chem 51: 5506-21 (2008) Article DOI: 10.1021/jm8002153 BindingDB Entry DOI: 10.7270/Q2PZ59QH
					More data for this Ligand-Target Pair