BDBM50253320 2-(4-(4-Fluorophenyl)-5-(2-(3-methylbutan-2-ylamino)pyridin-4-yl)-1H-imidazol-2-ylthio)ethanol::CHEMBL524174

SMILES: CC(C)C(C)Nc1cc(ccn1)-c1nc(SCCO)[nH]c1-c1ccc(F)cc1

InChI Key: InChIKey=WWSBAAXRYHTMOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50253320 (2-(4-(4-Fluorophenyl)-5-(2-(3-methylbutan-2-ylamin...) Show SMILES CC(C)C(C)Nc1cc(ccn1)-c1nc(SCCO)[nH]c1-c1ccc(F)cc1 Show InChI InChI=1S/C21H25FN4OS/c1-13(2)14(3)24-18-12-16(8-9-23-18)20-19(15-4-6-17(22)7-5-15)25-21(26-20)28-11-10-27/h4-9,12-14,27H,10-11H2,1-3H3,(H,23,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha (unknown origin)				J Med Chem 51: 5630-40 (2008) Article DOI: 10.1021/jm800373t BindingDB Entry DOI: 10.7270/Q2XS5V6V
					More data for this Ligand-Target Pair