BDBM50253478 1-Benzenesulfonyl-4-benzoyloxy-pyrrolidine-2-carboxylicacid methyl ester::CHEMBL523828

SMILES: COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)c1ccccc1)OC(=O)c1ccccc1

InChI Key: InChIKey=SJCLHSFAQZIWIL-WBVHZDCISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50253478 (1-Benzenesulfonyl-4-benzoyloxy-pyrrolidine-2-carbo...) Show SMILES COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)c1ccccc1)OC(=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19NO6S/c1-25-19(22)17-12-15(26-18(21)14-8-4-2-5-9-14)13-20(17)27(23,24)16-10-6-3-7-11-16/h2-11,15,17H,12-13H2,1H3/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 (unknown origin) by microtiter plate fluorimetric assay				Bioorg Med Chem 16: 7932-8 (2008) Article DOI: 10.1016/j.bmc.2008.07.073 BindingDB Entry DOI: 10.7270/Q2MP533K
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50253478 (1-Benzenesulfonyl-4-benzoyloxy-pyrrolidine-2-carbo...) Show SMILES COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)c1ccccc1)OC(=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19NO6S/c1-25-19(22)17-12-15(26-18(21)14-8-4-2-5-9-14)13-20(17)27(23,24)16-10-6-3-7-11-16/h2-11,15,17H,12-13H2,1H3/t15-,17+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of APN (unknown origin) by spectrophotometric assay				Bioorg Med Chem 16: 7932-8 (2008) Article DOI: 10.1016/j.bmc.2008.07.073 BindingDB Entry DOI: 10.7270/Q2MP533K
					More data for this Ligand-Target Pair