BDBM50253777 2-[2-(4-Carbamimidoylbenzyloxy)-4-methyl-3-oxo-N-phenyl-3,4-dihydro-2H-1,4-benzoxazine-7-carbonylamino]acetic acid::CHEMBL461417

SMILES: CN1C(=O)C(OCc2ccc(cc2)C(N)=N)Oc2cc(ccc12)C(=O)N(CC(O)=O)c1ccccc1

InChI Key: InChIKey=VFLMZJNMYXEIDM-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50253777 (2-[2-(4-Carbamimidoylbenzyloxy)-4-methyl-3-oxo-N-p...) Show SMILES CN1C(=O)C(OCc2ccc(cc2)C(N)=N)Oc2cc(ccc12)C(=O)N(CC(O)=O)c1ccccc1 Show InChI InChI=1S/C26H24N4O6/c1-29-20-12-11-18(24(33)30(14-22(31)32)19-5-3-2-4-6-19)13-21(20)36-26(25(29)34)35-15-16-7-9-17(10-8-16)23(27)28/h2-13,26H,14-15H2,1H3,(H3,27,28)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin)				J Med Chem 51: 5617-29 (2008) Article DOI: 10.1021/jm8003448 BindingDB Entry DOI: 10.7270/Q2JQ10TZ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50253777 (2-[2-(4-Carbamimidoylbenzyloxy)-4-methyl-3-oxo-N-p...) Show SMILES CN1C(=O)C(OCc2ccc(cc2)C(N)=N)Oc2cc(ccc12)C(=O)N(CC(O)=O)c1ccccc1 Show InChI InChI=1S/C26H24N4O6/c1-29-20-12-11-18(24(33)30(14-22(31)32)19-5-3-2-4-6-19)13-21(20)36-26(25(29)34)35-15-16-7-9-17(10-8-16)23(27)28/h2-13,26H,14-15H2,1H3,(H3,27,28)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.96E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				J Med Chem 51: 5617-29 (2008) Article DOI: 10.1021/jm8003448 BindingDB Entry DOI: 10.7270/Q2JQ10TZ
					More data for this Ligand-Target Pair
Integrin alpha-IIb (Homo sapiens (Human))	BDBM50253777 (2-[2-(4-Carbamimidoylbenzyloxy)-4-methyl-3-oxo-N-p...) Show SMILES CN1C(=O)C(OCc2ccc(cc2)C(N)=N)Oc2cc(ccc12)C(=O)N(CC(O)=O)c1ccccc1 Show InChI InChI=1S/C26H24N4O6/c1-29-20-12-11-18(24(33)30(14-22(31)32)19-5-3-2-4-6-19)13-21(20)36-26(25(29)34)35-15-16-7-9-17(10-8-16)23(27)28/h2-13,26H,14-15H2,1H3,(H3,27,28)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of fibrinogen binding to human platelet GPIIb/IIIa receptor				J Med Chem 51: 5617-29 (2008) Article DOI: 10.1021/jm8003448 BindingDB Entry DOI: 10.7270/Q2JQ10TZ
					More data for this Ligand-Target Pair