Found 5 hits for monomerid = 50254024 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM50254024
((+/-)-4'-Methoxy-biphenyl-3-sulfonic acid [2-[4-(2...)Show SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1 Show InChI InChI=1S/C30H38N4O4S/c1-38-27-10-8-25(9-11-27)26-6-3-7-28(20-26)39(36,37)33-29(19-23-4-2-5-24(18-23)21-32)30(35)34-16-13-22(12-15-31)14-17-34/h2-11,18,20,22,29,33H,12-17,19,21,31-32H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of matriptase (unknown origin) |
Bioorg Med Chem Lett 19: 67-73 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50254024
((+/-)-4'-Methoxy-biphenyl-3-sulfonic acid [2-[4-(2...)Show SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1 Show InChI InChI=1S/C30H38N4O4S/c1-38-27-10-8-25(9-11-27)26-6-3-7-28(20-26)39(36,37)33-29(19-23-4-2-5-24(18-23)21-32)30(35)34-16-13-22(12-15-31)14-17-34/h2-11,18,20,22,29,33H,12-17,19,21,31-32H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of plasmin (unknown origin) |
Bioorg Med Chem Lett 19: 67-73 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50254024
((+/-)-4'-Methoxy-biphenyl-3-sulfonic acid [2-[4-(2...)Show SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1 Show InChI InChI=1S/C30H38N4O4S/c1-38-27-10-8-25(9-11-27)26-6-3-7-28(20-26)39(36,37)33-29(19-23-4-2-5-24(18-23)21-32)30(35)34-16-13-22(12-15-31)14-17-34/h2-11,18,20,22,29,33H,12-17,19,21,31-32H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin (unknown origin) |
Bioorg Med Chem Lett 19: 67-73 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50254024
((+/-)-4'-Methoxy-biphenyl-3-sulfonic acid [2-[4-(2...)Show SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1 Show InChI InChI=1S/C30H38N4O4S/c1-38-27-10-8-25(9-11-27)26-6-3-7-28(20-26)39(36,37)33-29(19-23-4-2-5-24(18-23)21-32)30(35)34-16-13-22(12-15-31)14-17-34/h2-11,18,20,22,29,33H,12-17,19,21,31-32H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a (unknown origin) |
Bioorg Med Chem Lett 19: 67-73 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50254024
((+/-)-4'-Methoxy-biphenyl-3-sulfonic acid [2-[4-(2...)Show SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1 Show InChI InChI=1S/C30H38N4O4S/c1-38-27-10-8-25(9-11-27)26-6-3-7-28(20-26)39(36,37)33-29(19-23-4-2-5-24(18-23)21-32)30(35)34-16-13-22(12-15-31)14-17-34/h2-11,18,20,22,29,33H,12-17,19,21,31-32H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA (unknown origin) |
Bioorg Med Chem Lett 19: 67-73 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF |
More data for this Ligand-Target Pair | |