null

SMILES: FC(F)(F)c1ccc(Nc2nc(NCCN3CCOCC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1

InChI Key: InChIKey=QMDDHVPNWRIYII-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254079 (CHEMBL459320 | N2-(2,6-dichlorophenyl)-N5-(2-morph...) Show SMILES FC(F)(F)c1ccc(Nc2nc(NCCN3CCOCC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C24H22Cl2F3N7OS/c25-16-2-1-3-17(26)18(16)32-23-33-19-20(31-15-6-4-14(5-7-15)24(27,28)29)34-22(35-21(19)38-23)30-8-9-36-10-12-37-13-11-36/h1-7H,8-13H2,(H,32,33)(H2,30,31,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254079 (CHEMBL459320 | N2-(2,6-dichlorophenyl)-N5-(2-morph...) Show SMILES FC(F)(F)c1ccc(Nc2nc(NCCN3CCOCC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C24H22Cl2F3N7OS/c25-16-2-1-3-17(26)18(16)32-23-33-19-20(31-15-6-4-14(5-7-15)24(27,28)29)34-22(35-21(19)38-23)30-8-9-36-10-12-37-13-11-36/h1-7H,8-13H2,(H,32,33)(H2,30,31,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair