BDBM50254274 CHEMBL461440::N-{3-[(S)-2-[4-(2-Amino-ethyl)-piperidin-1-yl]-1-(3-carbamimidoyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide

SMILES: CCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1

InChI Key: InChIKey=CPCMZDILGQJEOE-QHCPKHFHSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50254274 (CHEMBL461440 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...) Show SMILES CCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1 |r| Show InChI InChI=1S/C26H36N6O4S/c1-2-24(33)30-21-7-4-8-22(17-21)37(35,36)31-23(16-19-5-3-6-20(15-19)25(28)29)26(34)32-13-10-18(9-12-27)11-14-32/h3-8,15,17-18,23,31H,2,9-14,16,27H2,1H3,(H3,28,29)(H,30,33)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of matriptase (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50254274 (CHEMBL461440 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...) Show SMILES CCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1 |r| Show InChI InChI=1S/C26H36N6O4S/c1-2-24(33)30-21-7-4-8-22(17-21)37(35,36)31-23(16-19-5-3-6-20(15-19)25(28)29)26(34)32-13-10-18(9-12-27)11-14-32/h3-8,15,17-18,23,31H,2,9-14,16,27H2,1H3,(H3,28,29)(H,30,33)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50254274 (CHEMBL461440 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...) Show SMILES CCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1 |r| Show InChI InChI=1S/C26H36N6O4S/c1-2-24(33)30-21-7-4-8-22(17-21)37(35,36)31-23(16-19-5-3-6-20(15-19)25(28)29)26(34)32-13-10-18(9-12-27)11-14-32/h3-8,15,17-18,23,31H,2,9-14,16,27H2,1H3,(H3,28,29)(H,30,33)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of plasmin (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50254274 (CHEMBL461440 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...) Show SMILES CCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1 |r| Show InChI InChI=1S/C26H36N6O4S/c1-2-24(33)30-21-7-4-8-22(17-21)37(35,36)31-23(16-19-5-3-6-20(15-19)25(28)29)26(34)32-13-10-18(9-12-27)11-14-32/h3-8,15,17-18,23,31H,2,9-14,16,27H2,1H3,(H3,28,29)(H,30,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of uPA (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50254274 (CHEMBL461440 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...) Show SMILES CCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1 |r| Show InChI InChI=1S/C26H36N6O4S/c1-2-24(33)30-21-7-4-8-22(17-21)37(35,36)31-23(16-19-5-3-6-20(15-19)25(28)29)26(34)32-13-10-18(9-12-27)11-14-32/h3-8,15,17-18,23,31H,2,9-14,16,27H2,1H3,(H3,28,29)(H,30,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
					More data for this Ligand-Target Pair