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BDBM50254292 2-((3S,5S)-5-(3-(aminomethyl)benzyl)-1-(biphenyl-4-ylmethyl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-3-yl)-N-(2-fluorobenzyl)acetamide::CHEMBL457245

SMILES: NCc1cccc(C[C@@H]2O[C@@H](CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(cc3)-c3ccccc3)c3ccccc23)c1

InChI Key: InChIKey=CHTPAWPHBCPSKZ-BCRBLDSWSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50254292   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50254292
PNG
(2-((3S,5S)-5-(3-(aminomethyl)benzyl)-1-(biphenyl-4...)
Show SMILES NCc1cccc(C[C@@H]2O[C@@H](CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(cc3)-c3ccccc3)c3ccccc23)c1 |r|
Show InChI InChI=1S/C39H36FN3O3/c40-34-15-6-4-13-32(34)25-42-38(44)23-37-39(45)43(26-27-17-19-31(20-18-27)30-11-2-1-3-12-30)35-16-7-5-14-33(35)36(46-37)22-28-9-8-10-29(21-28)24-41/h1-21,36-37H,22-26,41H2,(H,42,44)/t36-,37-/m0/s1
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Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



Vrije Universiteit Brussel

Curated by ChEMBL


Assay Description
Displacement of [125I]-[Leu8, DTrp22, Tyr25]-somatostatin-28 from human recombinant sst5 receptor expressed in chinese hamster CCL39 cells

J Med Chem 52: 95-104 (2009)


Article DOI: 10.1021/jm801205x
BindingDB Entry DOI: 10.7270/Q27W6D3B
More data for this
Ligand-Target Pair