BDBM50255035 (S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide::CHEMBL465934

SMILES: O=C(Cn1c2ccccc2n(-c2ccccn2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31

InChI Key: InChIKey=NPVWCAICMFQSJF-LJAQVGFWSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255035 ((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...) Show SMILES O=C(Cn1c2ccccc2n(-c2ccccn2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31 |r| Show InChI InChI=1S/C29H22N6O3/c36-25(17-34-22-7-1-2-8-23(22)35(28(34)38)24-9-3-4-12-30-24)32-20-11-10-18-15-29(16-19(18)14-20)21-6-5-13-31-26(21)33-27(29)37/h1-14H,15-17H2,(H,32,36)(H,31,33,37)/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255035 ((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...) Show SMILES O=C(Cn1c2ccccc2n(-c2ccccn2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31 |r| Show InChI InChI=1S/C29H22N6O3/c36-25(17-34-22-7-1-2-8-23(22)35(28(34)38)24-9-3-4-12-30-24)32-20-11-10-18-15-29(16-19(18)14-20)21-6-5-13-31-26(21)33-27(29)37/h1-14H,15-17H2,(H,32,36)(H,31,33,37)/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255035 ((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...) Show SMILES O=C(Cn1c2ccccc2n(-c2ccccn2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31 |r| Show InChI InChI=1S/C29H22N6O3/c36-25(17-34-22-7-1-2-8-23(22)35(28(34)38)24-9-3-4-12-30-24)32-20-11-10-18-15-29(16-19(18)14-20)21-6-5-13-31-26(21)33-27(29)37/h1-14H,15-17H2,(H,32,36)(H,31,33,37)/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair