BDBM50255037 CHEMBL463880::N-((S)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-3-(tetrahydrofuran-3-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide

SMILES: O=C(Cn1c2ccccc2n(C2CCOC2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31

InChI Key: InChIKey=ZBZITUCFAIMGPC-GPIXMLASSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255037 (CHEMBL463880 | N-((S)-2'-oxo-1,1',2',3-tetrahydros...) Show SMILES O=C(Cn1c2ccccc2n(C2CCOC2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31 |r| Show InChI InChI=1S/C28H25N5O4/c34-24(15-32-22-5-1-2-6-23(22)33(27(32)36)20-9-11-37-16-20)30-19-8-7-17-13-28(14-18(17)12-19)21-4-3-10-29-25(21)31-26(28)35/h1-8,10,12,20H,9,11,13-16H2,(H,30,34)(H,29,31,35)/t20?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255037 (CHEMBL463880 | N-((S)-2'-oxo-1,1',2',3-tetrahydros...) Show SMILES O=C(Cn1c2ccccc2n(C2CCOC2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31 |r| Show InChI InChI=1S/C28H25N5O4/c34-24(15-32-22-5-1-2-6-23(22)33(27(32)36)20-9-11-37-16-20)30-19-8-7-17-13-28(14-18(17)12-19)21-4-3-10-29-25(21)31-26(28)35/h1-8,10,12,20H,9,11,13-16H2,(H,30,34)(H,29,31,35)/t20?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255037 (CHEMBL463880 | N-((S)-2'-oxo-1,1',2',3-tetrahydros...) Show SMILES O=C(Cn1c2ccccc2n(C2CCOC2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31 |r| Show InChI InChI=1S/C28H25N5O4/c34-24(15-32-22-5-1-2-6-23(22)33(27(32)36)20-9-11-37-16-20)30-19-8-7-17-13-28(14-18(17)12-19)21-4-3-10-29-25(21)31-26(28)35/h1-8,10,12,20H,9,11,13-16H2,(H,30,34)(H,29,31,35)/t20?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair