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SMILES: CN1CCN(CC1)c1cc2c(Nc3ccc(F)cc3F)c(cnc2cc1F)C(N)=O

InChI Key: InChIKey=SOJLFDQBCPADMX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255646   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50255646
PNG
(4-(2,4-difluorophenylamino)-7-fluoro-6-(4-methylpi...)
Show SMILES CN1CCN(CC1)c1cc2c(Nc3ccc(F)cc3F)c(cnc2cc1F)C(N)=O
Show InChI InChI=1S/C21H20F3N5O/c1-28-4-6-29(7-5-28)19-9-13-18(10-16(19)24)26-11-14(21(25)30)20(13)27-17-3-2-12(22)8-15(17)23/h2-3,8-11H,4-7H2,1H3,(H2,25,30)(H,26,27)
PDB

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antibodypedia
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PC sid
UniChem

Similars
Article
PubMed
n/an/a 54n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of CSF1R (unknown origin)

Bioorg Med Chem Lett 19: 701-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV
More data for this
Ligand-Target Pair