null

SMILES: CCC(=O)N1CC[C@@H](C1)N1C(=O)N(Cc2cnc(Nc3ccc(N4CCN(C)CC4)c(C)c3)nc12)c1ccccc1OC

InChI Key: InChIKey=RWBFBLBCISYMOO-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50255829 (CHEMBL4070640) Show SMILES CCC(=O)N1CC[C@@H](C1)N1C(=O)N(Cc2cnc(Nc3ccc(N4CCN(C)CC4)c(C)c3)nc12)c1ccccc1OC |r| Show InChI InChI=1S/C32H40N8O3/c1-5-29(41)38-13-12-25(21-38)40-30-23(20-39(32(40)42)27-8-6-7-9-28(27)43-4)19-33-31(35-30)34-24-10-11-26(22(2)18-24)37-16-14-36(3)15-17-37/h6-11,18-19,25H,5,12-17,20-21H2,1-4H3,(H,33,34,35)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory of Respiratory Diseases , Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences , 190 Kaiyuan Avenue , Guangzhou 510530 , China. Curated by ChEMBL					Assay Description Inhibition of recombinant human wild type GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus using tyr4 peptide as su...				J Med Chem 61: 2353-2371 (2018) Article DOI: 10.1021/acs.jmedchem.7b01612 BindingDB Entry DOI: 10.7270/Q2NC63NB
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50255829 (CHEMBL4070640) Show SMILES CCC(=O)N1CC[C@@H](C1)N1C(=O)N(Cc2cnc(Nc3ccc(N4CCN(C)CC4)c(C)c3)nc12)c1ccccc1OC |r| Show InChI InChI=1S/C32H40N8O3/c1-5-29(41)38-13-12-25(21-38)40-30-23(20-39(32(40)42)27-8-6-7-9-28(27)43-4)19-33-31(35-30)34-24-10-11-26(22(2)18-24)37-16-14-36(3)15-17-37/h6-11,18-19,25H,5,12-17,20-21H2,1-4H3,(H,33,34,35)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory of Respiratory Diseases , Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences , 190 Kaiyuan Avenue , Guangzhou 510530 , China. Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus using tyr4 peptide as substrate af...				J Med Chem 61: 2353-2371 (2018) Article DOI: 10.1021/acs.jmedchem.7b01612 BindingDB Entry DOI: 10.7270/Q2NC63NB
					More data for this Ligand-Target Pair